OCULAR MANIFESTATIONS IN PATIENTS WITH PSORIASIS: A HOSPITALBASED CROSS-SECTIONAL STUDY
Authors: Dr. Sanjeev Lakra, Dr. Vandana Mahaur*, Dr. TS Ahluwalia, Dr. Rajender Devanda
Publication Date: 2026/09/23
DOI: 10.59551/10.59551/IJHMP/25832069/2026.7.2.160
Abstract
<p>Background: Psoriasis is a chronic immune-mediated inflammatory disorder that may involve the ocular surface, adnexa, and intraocular structures. Even though ocular manifestations have a considerable morbidity, the diagnosis is often missed. Early identification is key to avoid sight-threatening issues and enhance quality of life. Objective: To assess the spectrum of ocular manifestations in patients with psoriasis.</p>
<p>Methods: This was an observational cross sectional study carried out in the Department of Ophthalmology and Dermatology of National Institute of Medical Sciences and Research, Jaipur. There were 42 patients with psoriasis who were enrolled study was conducted between March 2024 and September 2025. The eye exam was detailed, and involved slit lamp biomicroscopy , and scoring for the Standard Patient Evaluation of Eye Dryness (SPEED) questionnaire. Descriptive statistics were used for data analysis and p <0.05 was set as the level of statistical significance.</p>
<p>Results: The mean age of participants was 37.59 ± 18.57 years, with 20 males (47.6%) and 22 females (52.4%). 15 patients (35.7%) had blepharitis. Conjunctival hyperemia was the most common finding, seen in 31 patients (73.8%) (p<0.001). Dry-eye severity based on SPEED score was normal in 11 (26.2%), mild in 11 (26.2%), moderate in 6 (14.3%), and severe in 14 patients (33.3%) (p=0.002). Corneal involvement was noted in 10 patients (23.8%) (p=0.018). Episcleritis was seen in 4.8% (2) while uveitis was observed in 4.8% (2) (p=0.317).</p>
<p>Conclusion: Ocular manifestations in psoriasis predominantly involved the ocular surface and adnexa. A substantial proportion of patients were asymptomatic despite objective ocular findings. Regular ophthalmic screening should therefore be considered in patients with psoriasis. The most common signs or symptoms found were conjunctival hyperemia, dry eye disease and blepharitis. Patients with psoriasis are recommended to receive routine ophthalmic screening and a multidisciplinary approach for their care.</p>
<p>KEYWORDS: Psoriasis, Dry Eye Disease, Blepharitis, Conjunctival Hyperemia, Uveitis, Ocular Manifestations.</p>
References
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